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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD2
All Species:
4.55
Human Site:
S135
Identified Species:
16.67
UniProt:
Q9BYW2
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BYW2
NP_054878.5
2564
287550
S135
E
E
S
S
P
P
K
S
R
V
E
L
G
K
I
Chimpanzee
Pan troglodytes
XP_516423
2549
285788
K130
E
L
G
K
I
H
F
K
K
H
L
L
H
V
T
Rhesus Macaque
Macaca mulatta
XP_001113652
2550
286209
K126
K
S
R
V
E
L
G
K
I
H
F
K
K
H
L
Dog
Lupus familis
XP_864158
2562
287091
S135
E
E
S
S
P
P
K
S
R
V
E
L
G
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418510
2354
262767
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783359
3042
342758
G158
V
N
D
K
T
A
K
G
P
S
L
Q
D
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q2LAE1
1759
193210
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.9
92
N.A.
N.A.
N.A.
N.A.
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.7
Protein Similarity:
100
98.9
98
94.6
N.A.
N.A.
N.A.
N.A.
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.6
P-Site Identity:
100
13.3
0
100
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
13.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
0
0
0
0
15
0
0
% D
% Glu:
43
29
0
0
15
0
0
0
0
0
29
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
15
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
15
0
0
0
15
15
0
0
0
0
29
0
0
% G
% His:
0
0
0
0
0
15
0
0
0
29
0
0
15
15
0
% H
% Ile:
0
0
0
0
15
0
0
0
15
0
0
0
0
0
29
% I
% Lys:
15
0
0
29
0
0
43
29
15
0
0
15
15
29
0
% K
% Leu:
0
15
0
0
0
15
0
0
0
0
29
43
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
29
29
0
0
15
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
0
15
0
0
0
0
0
29
0
0
0
0
0
0
% R
% Ser:
0
15
29
29
0
0
0
29
0
15
0
0
0
15
0
% S
% Thr:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
15
% T
% Val:
15
0
0
15
0
0
0
0
0
29
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _